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Ramadan Β· Clinical guidance

The Ramadan Protocol for GLP-1 users

Fasting during Ramadan while on semaglutide, tirzepatide or another GLP-1 medication changes the timing of everything β€” meals, hydration and side-effect windows. These are educational pointers to discuss with your physician, not a prescription.

Six things to plan

A calmer, safer fasting month

1

Plan your dose timing with your physician

Weekly GLP-1 injections do not need to line up with a specific meal, but many people prefer to inject on a non-fasting day or in the evening after iftar so any early nausea passes overnight. Do not change your dose or day yourself β€” agree it with your prescribing doctor before Ramadan begins.

2

Hydrate deliberately between iftar and suhoor

GLP-1 medications blunt appetite and thirst, so it is easy to under-drink during the short non-fasting window. Aim to sip water steadily from iftar through to suhoor rather than in one or two large amounts, and limit heavily caffeinated or very sugary drinks that can worsen dehydration.

3

Break the fast gently β€” GLP-1 slows gastric emptying

Because these medications slow how quickly the stomach empties, a large, fast iftar can bring on bloating, reflux or nausea. Open with water and a couple of dates, pause, then eat a modest, balanced meal slowly. A smaller iftar followed by a light later meal is often more comfortable than one heavy plate.

4

Keep electrolytes and protein in mind at suhoor

Long fasting hours plus reduced intake can leave you low on fluids and electrolytes. A suhoor with adequate salt, potassium-rich foods and protein helps you stay hydrated and protects muscle mass, which matters especially for anyone losing weight on a GLP-1.

5

Watch for hypoglycaemia if you take other medications

GLP-1 medicines alone rarely cause low blood sugar, but combined with insulin or sulfonylureas the risk during a fast rises. Know the signs β€” shakiness, sweating, confusion, palpitations β€” and speak to your doctor beforehand about whether those other medications need adjusting for Ramadan.

6

See your physician before Ramadan to adjust the plan

The single most useful step is a pre-Ramadan review. Your doctor can decide whether to hold, delay or re-time a dose, review interacting medications, and set clear rules for when to break your fast on medical grounds. This guide never replaces that conversation.

Note: This page is general education only and is not medical advice. It does not tell you whether it is safe for you to fast. Always consult your DHA- or DOH-licensed physician before making any change to your medication, dose or fasting plan during Ramadan.

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